Tetrapyrroles and derivatives
Abcam Rotigotine hydrochloride, Dopamine receptor agonist, 50MG
MW 351.93 g/mol, Purity >99%. Dopamine receptor agonist. High affinity for D₁, D₂ and D₃ receptors (Ki values are 83, 13 and 0.71 nM, respectively). Shows significant affinity at α₂B and 5-HT₁A receptors (Ki values are 27 and 30 nM, respectively). Exhibits anti-Parkinsonian and antidepressant activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-745870 trihydrochloride, brain penetrant D4 antagonist, 50MG
MW 436.21 g/mol, Purity >99%. Highly potent and selective D₄ antagonist (Ki values are 0.43, 2300 and 960 nM at D₄, D₃ and D₂, respectively). Brain permeable. Inhibits cell death and shows neuroprotective effects.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from equine heart suitable for GFC marker, BioReagent | 9007-43-6 | MFCD00130890 | 1VL
Cytochrome c from equine heart suitable for GFC marker, BioReagent | 9007-43-6 | MFCD00130890 | 1VL
Enzo Life Sciences Zinc(II) Protoporphyrin IX (100mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Appearance: Dark solid. Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.
Enzo Life Sciences Protoporphyrin IX (free acid) (300mg). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
eMolecules Zinc phthalocyanine | 14320-04-8 | MFCD00041955 | 25g
Combi-Blocks | Zinc phthalocyanine | 25g | 296392447 | QC-0016 | 95.000 | 14320-04-8 | MFCD00041955 | 577.920 | C32H16N8Zn
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Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from bovine heart | 9007-43-6 | MFCD00130890 | 250 mg
Cytochrome c from bovine heart | Purity: ≥95% | Mol Wt: 12327 Da | 9007-43-6 | MFCD00130890 | 250 mg
Frontier Specialty Chemicals 50MG 5-MONO(4-CARBOXYPHENYL)-1
5-mono(4-carboxyphenyl)-10,15,20-triphenyl porphyrin; CAS: 95051-10-8; 50mg
Abcam Flupenthi x ol dihydrochloride, Non-selective dopamine receptor antagonist, 50MG
MW 507.4 Da, Purity >99%. Non-selective antagonist at D₁ and D₂ receptors. Antagonist at dopamine (D₁-D₅), serotonin (5-HT₂), adrenergic (α₁) and histamine (H₁) receptors. Antipsychotic properties in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PNU 120596, Positive allosteric modulator for alpha7 nicotinic acetylcholine receptors, 10MG
MW 311.72 Da, Purity >99%. Competitive, type II positive allosteric modulator for α7nAChR (EC₅₀ = 216 nM). Increases potency of nicotinic agonists. No effect on α4β2, α3β4 and α9α10 nAChRs. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist, 10MG
MW 732.7 Da. Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine (ab120469) from nAChRs (IC₅₀ = 5.5 nM). Neuromuscular blocker and muscle relaxant.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist, 50MG
MW 732.7 Da. Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine (ab120469) from nAChRs (IC₅₀ = 5.5 nM). Neuromuscular blocker and muscle relaxant.
The product is subject to the following: Abcam Restricted Use Statement
eMolecules 3-Hydroxy-4-methyl-2(3H)-thiazolethione | 49762-08-5 | MFCD00077793 | 5g
Combi-Blocks, Inc. | 3-Hydroxy-4-methyl-2(3H)-thiazolethione | 5g | 603151825 | QA-9143 | 95.000 | 49762-08-5 | MFCD00077793 | 147.210 | C4H5NOS2
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![eMolecules Medchem Express / Biliverdin (hydrochloride) / 5mg / 788478200 / HY-135005 / / 856699-18-8 / [null] / 619.120 / C33H35ClN4O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502463383.JPG-250.jpg)
eMolecules Medchem Express / Biliverdin (hydrochloride) / 5mg / 788478200 / HY-135005 / / 856699-18-8 / [null] / 619.120 / C33H35ClN4O6
Medchem Express / Biliverdin (hydrochloride) / 5mg / 788478200 / HY-135005 / / 856699-18-8 / [null] / 619.120 / C33H35ClN4O6